Stephan Kemp Selected Research

Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)

1/2022	Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.
1/2022	Structure and Function of the ABCD1 Variant Database: 20 Years, 940 Pathogenic Variants, and 3400 Cases of Adrenoleukodystrophy.
12/2021	Molecular Biomarkers for Adrenoleukodystrophy: An Unmet Need.
1/2021	Corrigendum: Adrenoleukodystrophy Newborn Screening in the Netherlands (SCAN Study): The X-Factor.
1/2021	The brain penetrant PPARγ agonist leriglitazone restores multiple altered pathways in models of X-linked adrenoleukodystrophy.
1/2021	Metabolic rerouting via SCD1 induction impacts X-linked adrenoleukodystrophy.
1/2021	Endocrine dysfunction in adrenoleukodystrophy.
1/2021	iBRET Screen of the ABCD1 Peroxisomal Network and Mutation-Induced Network Perturbations.
11/2020	Targeting foam cell formation in inflammatory brain diseases by the histone modifier MS-275.
11/2020	Plasma NfL and GFAP as biomarkers of spinal cord degeneration in adrenoleukodystrophy.

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Stephan Kemp Research Topics

Disease

45	Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked) 01/2022 - 08/2002
13	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 08/2002
4	Demyelinating Diseases (Demyelinating Disease) 01/2021 - 10/2006
4	Spinal Cord Diseases 01/2020 - 03/2015
3	Adrenal Insufficiency (Adrenal Gland Hypofunction) 01/2019 - 06/2008
2	Disease Progression 12/2021 - 01/2019
2	Peroxisomal Disorders (Peroxisomal Disorder) 01/2021 - 01/2020
2	Inflammation (Inflammations) 01/2021 - 11/2013
2	Inborn Errors Metabolism (Inborn Errors of Metabolism) 01/2019 - 01/2016
2	Sjogren-Larsson Syndrome 02/2009 - 06/2008
2	Neuroblastoma 10/2005 - 10/2004
1	Pain (Aches) 01/2022
1	Multiple Sclerosis 11/2020
1	Brain Diseases (Brain Disorder) 11/2020
1	Neuroinflammatory Diseases 11/2020
1	Metabolic Diseases (Metabolic Disease) 01/2012
1	Coma (Comas) 06/2011
1	Mitochondrial Encephalomyopathies (Mitochondrial Encephalomyopathy) 09/2009
1	Hepatocellular Carcinoma (Hepatoma) 03/2006
1	Neoplasms (Cancer) 10/2004

Drug/Important Bio-Agent (IBA)

29	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 08/2002
8	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2019 - 08/2002
7	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2006
5	Biomarkers (Surrogate Marker)IBA 12/2021 - 01/2016
5	Member 1 Subfamily D ATP Binding Cassette TransporterIBA 01/2021 - 03/2010
4	Adenosine Triphosphate (ATP)IBA 01/2022 - 05/2003
3	Histone Deacetylases (Histone Deacetylase)IBA 11/2020 - 10/2004
3	Histone Deacetylase InhibitorsIBA 01/2020 - 10/2004
3	BezafibrateIBA 02/2015 - 01/2012
2	hexachlorocyclohexane x-factorIBA 01/2021 - 01/2020
2	LipidsIBA 11/2020 - 01/2017
2	Histones (Histone)IBA 11/2020 - 10/2004
2	Lysophosphatidylcholines (Lysophosphatidylcholine)IBA 01/2020 - 12/2017
2	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 10/2006
2	Carnitine (L-Carnitine)FDA LinkGeneric 12/2017 - 01/2016
2	EnzymesIBA 01/2012 - 08/2002
2	Membrane Proteins (Integral Membrane Proteins)IBA 06/2011 - 05/2003
2	long-chain-aldehyde dehydrogenaseIBA 02/2009 - 06/2008
2	BL1521IBA 10/2005 - 10/2004
2	long-chain-fatty-acid-CoA ligaseIBA 05/2003 - 08/2002
1	leriglitazoneIBA 01/2021
1	Biological ProductsIBA 01/2021
1	Adenosine (Adenocard)FDA LinkGeneric 01/2021
1	Neuroprotective AgentsIBA 01/2021
1	Glial Fibrillary Acidic ProteinIBA 11/2020
1	entinostat (MS 275)IBA 11/2020
1	Vorinostat FDA Link 01/2020
1	Fibric Acids (Fibrates)IBA 02/2015
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 11/2013
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 11/2012
1	Pharmaceutical PreparationsIBA 01/2012
1	Initiator Codon (Start Codon)IBA 12/2011
1	Subfamily D ATP Binding Cassette TransporterIBA 06/2011
1	AntioxidantsIBA 05/2010
1	hexacosanoic acidIBA 05/2010
1	Valproic Acid (Depakote)FDA LinkGeneric 05/2010
1	Lovastatin (Mevacor)FDA LinkGeneric 01/2010
1	Fatty AlcoholsIBA 02/2009
1	NAD (NADH)IBA 06/2008
1	Alcohol Dehydrogenase (Alcohol Dehydrogenase (NAD+))IBA 06/2008
1	Cystathionine beta-Synthase (Serine Sulfhydrase)IBA 10/2006
1	Methionine (L-Methionine)FDA Link 10/2006
1	OligonucleotidesIBA 10/2005
1	Lorenzo's oilIBA 02/2005
1	CarbonIBA 05/2003

Therapy/Procedure

3	Therapeutics 12/2021 - 01/2019
2	Aftercare (After-Treatment) 01/2021 - 10/2005
2	Hematopoietic Stem Cell Transplantation 01/2020 - 12/2017
1	Cell Transplantation 03/2015
1	Drug Therapy (Chemotherapy) 10/2004